Therapeutic Use of Mitochondrial Fusion Promoter M1 for Nervous System Injury
The inventors identified mitochondrial fusion promoter M1 as a potent small molecule that has the therapeutic potential to enhance the intrinsic growth capacity of adult neurons—an important step as successful axon regeneration after nervous system injuries largely depends on the intrinsic growth capacity of injured neurons.
- Mitochondrial Fusion Promoter
- Axon Regeneration
- Potent Small Molecule
- Neuron Intrinsic Growth
- Central Nerve Injury
- Peripheral Nerve Injury
Artificial Intelligence (AI) and Machine Learning (ML) Based Encephalogram (EEG) Platform for Drug’s Screening
The inventors established EEG electrode implantation in mice model of epilepsy and Video-EEG were recorded. Seizure symptoms of epilepsy were evaluated using video recording and correlated with corresponding EEG activity through the developed Artificial Intelligence (AI) and Machine learning (ML) platform as preclinical study.
- Artificial Intelligence
- Machine Learning
- Investigational New Drug
- Convolutional Neural Network
- Drug Screening
- Preclinical Studies
- Neurodegenerative Disease
Neural Motor prosthesis Prototype for the Restoration of Motor Function in Spinocerebellar Ataxia
SCA is a neurodegenerative disease characterized by motor function deficits. Deep brain stimulation (DBS) has been widely used in treating neurodegenerative diseases with motor deficits such as Parkinson’s disease.
- Next Generation Deep brain stimulation
- Closed-loop Deep brain stimulation
Low-dose Radiation Therapy for Traumatic Brain Injury and Stroke
The invention is to provide the therapeutic potential of whole-body low dose X-ray irradiation in promoting motor functional recovery after TBI and stroke.
- Low-dose X-ray irradiation
- Traumatic brain injury
- Ischemic stroke
- Novel treatment