Research Grants Awarded in the Past Year (2019-20)

Early Career Scheme

Principal Investigator Project Title
Dr KWOK Chun Kit Studying the Effect of RNA G-quadruplex Structure on Precursor MicroRNA Processing and Post-transcriptional Regulation
Dr LY Thuc Hue The Patterned Functionalization of Graphene and Transitional Metal Dichalcogenides for Optoelectronics
Dr MATSUDA Yudai Comprehensive Understanding and Engineering of Fungal Xanthone Biosynthesis
Dr ZHU Zonglong Compositional and Interfacial Engineering for Highly Efficient Perovskite Solar Cells with Extremely Low Voltage Loss
Dr PENG Yung-Kang Identifying the Chemical State of Cerium Hosted by Various CeO2 Facets as Surface Fingerprint and Its Facet-dependent Phosphatase-mimetic Activity

General Research Fund

Principal Investigator Project Title
Dr SUN Hongyan Peptide-based Tools for Investigating Protein Tyrosine Phosphatases Involved in Parkinsons Disease
Dr CHEUNG Siu Gin Microplastic Pollution in Hong Kong and Its Effects on Energetics of Sandy Shore Bivalves
Dr KO Chi Chiu Vincent Design, Synthesis and Application of Luminescent Transition Metal Complexes for Photocatalytic Activation of Carbon Dioxide
Prof LEE Chun Sing Effects of Transition Metal Oxide Doping on Delocalized Charge Density and Charge Energetics at Organic Donor/acceptor Interfaces
Prof XU Zhengtao Highly Recyclable, Bona Fide Heterogeneous Catalysis by Dangling Metal-sulfur Functions within Robust Porous Solids
Dr WONG Chun Yuen Alex Detecting Protein Tyrosine Kinase-7 Using Nanowire Biosensor
Prof LO Kam Wing Kenneth Strategic Utilization of the Photophysical and Photochemical Properties of Luminescent Transition Metal Complexes as Synthetic Substrates for Protein Tags
Prof LEE Chun Sing Photocharge-Modulated Photoemission Spectroscopy and its Applications for Characterizing Organic Donor-Acceptor Junction
Dr SUN Hongyan Developing Novel Fluorescent Probes for Detecting Histone Deacetylase Activity
Prof LAU T C Seven-Coordinate Metal Oxo and D0 Metal Nitrido Oxo Complexes as Active Species for the Oxidation of Water and Organic Substrates
Prof KWONG Hoi Lun Design and Synthesis of Chiral-at-Metal Complexes for Asymmetric Catalysis
Prof LAM Kwan Sing Paul Environmental Assessment of Chiral Pharmaceuticals in Hong Kong and its Surrounding Region: Occurrence, Fate and Potential Toxicological Significance
Prof LAM Hon Wah Michael Mechanistic Studies of Photo-triggered Traceless Staudinger-Bertozzi Ligation Reaction
Dr AU Wai Ting Doris Unraveling the Epigenetic Pathways Underlying Transgenerational Vertebral Deformity Induced by Benzo[a]pyrene Using Unique Transgenic Medaka Bone Model
Dr WONG Chun Yuen Alex Rational Design of Photoresponsive Anti-Cancer Drug Delivery Nanoparticles
Prof LO Kam Wing Kenneth Exploitation of Luminescent Transition Metal Perfluoroarene Complexes as Novel Biological Probes for Peptide Tags and Their Applications in Site-Specific Bioconjugation, Live-Cell Imaging, and Photoinduced Inactivation of Proteins
Dr SIU Chi Kit Andy Sequence, Proximity and Electronic Factors Affecting Electron Transfers from the N-terminal Amino Group to the π-radical Tautomer of Tyrosine Residue in Molecular Peptide Radical Cations in the Gas Phase
Dr KONG Yuen Chong Richard Integrated Chemical-biological Processes to Enhance Remediation of Estuarine Sediments Contaminated with Polybrominated Diphenylethers (PBDEs)
Prof LAU T C Synthesis and Reactivity of Electrophilic Manganese(VI) Imido and Chromium(VI) Nitrido and Imido Complexes
Prof CHAN Michael Chi Wang Topologically Tunable Bimetallic Platforms: Design and Development of Catalytic and Cooperative Reactivity
Dr KO Chi Chiu Vincent Design of Acyclic Carbene Complexes for Catalytic and Sensing Applications
Dr KWOK Chun Kit Interrogating the Effect of 3'UTR RNA G-quadruplex Structure in MicroRNA Target Site Accessibility and Translational Regulation
Dr KONG Yuen Chong Richard Modulation of Androgen Receptor Signaling by miRNAs: A Molecular Basis for Hypoxia-induced Male-biased Sex Ratios in Fish
Prof LO Kam Wing Kenneth Development of Silsesquioxane-based Molecular Materials Modified with Luminescent Transition Metal Complexes as a New Nanoplatform for Bioimaging and Therapeutic Applications
Prof LEE Chun Sing Role of Charge- And Energy-Transfer Processes in Ternary Organic Photovoltaic Devices
Prof LAU T C Synthesis and Reactivity of Iron(VI) Nitrido Complexes
Dr KO Chi Chiu Vincent Design, Synthesis and Study of Re(I) and Ir(III) Complexes with CAAC Ligands
Dr SUN Hongyan Developing Chemical Tools for Studying Delipoylating Enzymes
Dr ZHU Guangyu Synthesis, Mechanistic Study, and Biological Evaluation of Visible Light-activatable Platinum(IV) Anticancer Prodrugs
Prof XU Zhengtao Porous Carbon Networks from Domino Linker Cyclization of Metal-Organic Framework Precursors
Dr LAU Kai Chung ab initio Composite Procedure for Accurate Prediction of Standard Redox Potentials
Dr KWOK Chun Kit Mapping and Targeting of RNA G-quadruplex Structures in the Human Non-coding Transcriptome
Dr SUN Hongyan Peptide Self-assembly Tools for Detecting Sirt5 Activity in Living Cells
Prof LO Kam Wing Kenneth Phosphorogenic Bioorthogonal Probes Derived from Transition Metal Complexes as New Bioimaging Reagents and Photofunctional Therapeutic Agents
Prof LEE Chun Sing Novel Properties of Organic Charge-transfer Complexes under Photoexcitation
Dr LAI Keng Po Gut Microbiota Links Bisphenol A to Metabolic Syndrome
Prof XU Zhengtao Post-synthetic Integration of Strong Donor-acceptor Functions for Electroactive Metal-organic Frameworks
Dr SIU Chi Kit Andy Theoretical Examinations for the Dissociative Electron Transfers of the Prototypical Disulfide Linkage with a Hydrated Electron and Carbon Dioxide Radical Anion in Water Clusters and Aqueous Solution
Dr LO Pik Kwan Peggy Design, Assembly and Operations of a Series of Photochemically Controlled DNA Logic Devices
Prof LAM Hon Wah Michael Assembling Molecular Machines into Organometallic Polymers
Dr KO Chi Chiu Vincent Design, Synthesis and Study of Luminescent Transition Metal Carbene Complexes with Mechanochromic Behaviour
Dr ZHU Guangyu Development and Mechanistic Investigation of Nucleus-targeting Platinum(IV) Prodrugs for Improved Anticancer Activity

 

Collaborative Research Fund

Principal Investigator Project Title
Prof LAM Kwan Sing Paul Benthic and Epiphytic Toxic Algae (BETA): An Emerging Threat to Coral Ecosystems in Hong Kong Waters
Prof LEE Chun Sing Multi-function Analytical Facility with Time-resolved Two-photon Photoemission (TR-2PPE) Spectroscopy
Prof LO Kam Wing Kenneth Aggregation-Induced Emission (AIE): Development of New AIE Systems and Exploration of Their Biomedical Applications

France/HK Joint Research Scheme

Principal Investigator Project Title
Prof LO Kam Wing Kenneth AQUACULUM - Design of Water-Soluble Luminescent Copper(I) Polymetallic Supramolecular Assemblies as Novel Cellular Reagents for Bioimaging and Photocytotoxic Applications

 

Innovation and Technology Commission — Innovation and Technology Fund

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Principal Investigator Project Title
Dr ZHU Guangyu Preclinical In vivo Evaluation of a Water-Soluble and Potent Platinum-Based Anticancer Prodrug
Dr KO Chi Chiu Vincent Development of Printable Electrodes for Simultaneous Monitoring Five Targeted Metal Ions in Water
Prof LEE Chun Sing Preparation of Self-assembled Nanodrugs (SANDs) by an Ice-template Assisted Method
Dr WONG Chun Yuen Alex Developing Novel Chromones and Photo-Triggered Chromone Delivery System for Cosmetic Applications
Prof HORVATH Istvan Tamas Assessment of the Sustainability of Fluorous Compounds with Short-Chain Perfluoroalkyl Groups
Dr KO Chi Chiu Vincent Development of Novel Polymer-Based Oral Sequestrants for Treatment of Cardiometabolic Diseases
Dr WONG Chun Yuen Alex Development of Solid, Packaging-free, 2-in-1 Shampoo & Conditioner Bars with a Novel Formulation
Prof JEN Alex Rational Design of Efficient and Stable Transporting Materials for High Efficiency Metal Halide Perovskite Solar Cells and Large-Scale Fabrication
Prof LEE Chun Sing Stable Organic Nanoparticles With High Photothermal Energy Conversion Efficiencies For Biomedical And Energy Applications

 

Environmental and Conservation Fund

Principal Investigator Project Title
Dr CHEUNG Siu Gin ECF “Shui Hau Magnification” – Understanding Human Disturbances on Horseshoe Crabs
Dr CHEN Jianlin A Dye-assisted Paper-based Assay for Fast and Reliable Detection of Biotoxicity for Anaerobic Digestion
Dr CHEUNG Siu Gin Microplastics Accumulate and Transfer Persistent Organic Pollutants to Hong Kong Marine Fish
Dr CHEUNG Siu Gin To Fill the Knowledge Gap in the Distribution of Juvenile Horseshoe Crabs in Hong Kong and Determine the Mortality and Growth of Laboratory-reared Juveniles after being Released to the Wild

Health and Medical Research Fund

Principal Investigator Project Title
Dr LO Pik Kwan Peggy Overcoming Blood-Brain Barrier to Treat Brain Cancers by Multifunctional Nanodiamond-Mediated Drug Delivery System
Dr LAM Yun Wah A New Class of Antimicrobial Therapeutics That Targets the Envelope Stress Response of Gram-negative Bacteria

 

Research Projects funded by the Mainland Government

Principal Investigator Project Title
Dr ZHU Zonglong 全无机钙钛矿光伏器件中的材料设计及光电性能研究
Prof JEN Alex 粤港澳光电磁功能材料联合实验室
Prof LAM Kwan Sing Paul 南海海岸带变化与物质迁移

Contract Research-RO

Principal Investigator Project Title
Prof LAM Kwan Sing Paul Provision of Services for Laboratory Analysis of Antibiotics in Ambient River and Marine Water Samples
Prof LAM Kwan Sing Paul Study of the Ecological Impact on the Use of Recycled Water
Prof HORVATH Istvan Tamas Synthesis of 13C-labelled Alkyl-and Aryl-isocyanates and Their Use in Mechanistic Studies of Oligomerization of Alkyl-and Aryl-isocyanates in the Presence or Absence of Carbon Dioxide
Prof CHAN Michael Chi Wang Collaborative Materials and Catalysis Research
Dr CHEUNG Siu Gin Juvenile Horseshoe Crab Rearing Programme 2018/2019
Dr CHEUNG Siu Gin Juvenile Horseshoe Crab Rearing Programme 2019/2020
Dr KONG Yuen Chong Richard Ancestral Exposure to Environmental Benzo[a]pyrene Causes Transgenerational Bone Impairment in Fish: Underlying Mechanisms at the Genetic and Epigenetic Level
Prof LAM Hon Wah Michael Development of "Electronic Tongues" for in situ Monitoring of Endocrine Disrupting Chemicals in the Marine Environment
Prof LAM Kwan Sing Paul Non-target Screening and Ecological Risk Assessment of Emerging Chemicals of Concern in Marine Cetaceans from the South China Sea

Croucher Foundation Research Grant

Principal Investigator Project Title
Dr KWOK Chun Kit Croucher Start-up Allowance for Dr Kwok Chun Kit