Skip to navigation
Skip to content
Recent Publications
Wan, Y. C. E. & Chan, K. M. (2021). Histone H2B Mutations in Cancer. Biomedicines, 9(6): 694.

doi: 10.3390/biomedicines9060694
Wang, P., Al Azad, M. A. R., Yang, X., Martelli, P. R., Cheung, K. Y., Shi, J. & Shen, Y. (2021). Self-adaptive and efficient propulsion of Ray sperms at different viscosities enabled by heterogeneous dual helixes. Proceedings of the National Academy of Sciences Jun 2021, 118: 23 e2024329118.

doi: 10.1073/pnas.2024329118
Zhou, F., Wan, Q., Chen, Y., Chen, S. & He, M.L. (2021). PIM1 kinase facilitates Zika virus replication by suppressing host cells' natural immunity. Signal Transduct Target Ther. 6(1):207.

doi: 10.1038/s41392-021-00539-x
Kandimalla, R., Wang, W., Yu, F., Zhou, N., Gao, F., Spillman, M., Moukova, L., Slaby, O., Salhia, B., Zhou, S., Wang, X. & Goel, A. (2021). OCaMIR - A noninvasive, diagnostic signature for early stage ovarian cancer: a multi-cohort retrospective and prospective study. Clinical Cancer Research, published online 25 May 2021.

doi: 10.1158/1078-0432.CCR-21-0267
Huang, H., Hu, J., Maryam, A., Huang, Q., Zhang, Y., Ramakrishnan, S., Li, J., Ma, H., Ma, V. W. S., Cheuk, W., So, G. Y. K., Wang, W., Cho, W. C. S., Zhang, L., Chan, K. M., Wang, X. & Chin, Y. R. (2021). Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling. Nature Communications, 12: 2242.

doi: 10.1038/s41467-021-2244 c5-0
Wang, T., Sun, W., Fan, L., Hua, C., Wu, N., Fan, S., Zhang, J., Deng, X. & Yan, J. (2021). An atlas of the binding specificities of transcription factors in Pseudomonas aeruginosa directs prediction of novel regulators in virulence. eLife, 10: e61885.

doi: 10.7554/eLife.61885
Shao, X., Tan, M., Xie, Y., Yao, C., Wang, T., Huang, H., Zhang, Y., Ding, Y., Liu, J., Han, L., Hua, C., Wang, X. & Deng, X. (2021). Integrated regulatory network in Pseudomonas syringae reveals dynamics of virulence. Cell Reports, 34: 108920.

doi: 10.1016/j.celrep.2021.108920
Kang, T. Z. E., Zhu, L., Yang, D., Ding, D., Zhu, X., Wan, Y. C. E., Liu, J., Ramakrishnan, S., Chan, L. L., Chan, S. Y., Wang, X., Gan, H., Han, J., Ishibashi, T. Li, Q. & Chan, K. M. (2021). The elevated transcription of ADAM19 by the oncohistone H2BE76K contributes to oncogenic properties in breast cancer. Journal of Biological Chemistry, published online 4 Feb 2021.

doi: 10.1016/j.jbc.2021.100374
Yan, J., Qiu, Y., Ribeiro dos Santos, A.M. et al. (2021). Systematic analysis of binding of transcription factors to noncoding variants. Nature, published online 27 Jan 2021.

doi: 10.1038/s41586-021-03211-0
Vacancies
Faculty Positions Available
Research Degree Programmes
Research Openings
Technical Posts
All Vacancies
Useful Links
Campus Map
Committee Against Sexual Harassment (CASH)
Contact Us
CityU Virtual Information Day 2021

Upcoming Webinar

Cabozantinib overcomes ABCG2-mediated drug resistance in cancer
Prof. Zhe-Sheng (Jason) Chen, St. John’s University, USA
 10 July 2021 (Saturday) · 9:30 pm 9:30 am · via Zoom

See all seminars

News

Tung Biomedical Sciences Centre at CityU established and named in recognition of The Tung Foundation
19 Aug 2021 Tung Biomedical Sciences Centre at CityU established and named in recognition of The Tung Foundation
CityU is continuously pursuing academic and research excellence to create a better future. In 2020 and 2021, when the world faces unprecedented challenges in public health, with the generous support of The Tung Foundation, CityU has proudly launched the Tung Biomedical Sciences Centre...
Tung Biomedical Sciences Centre at CityU established and named in recognition of The Tung Foundation
19 Aug 2021 Tung Biomedical Sciences Centre at CityU established and named in recognition of The Tung Foundation
The newly established Tung Biomedical Sciences Centre at CityU has been named in honour of The Tung Foundation in appreciation of the staunch and generous support of the Foundation...
Animal experiments demonstrated the need for new cochlear implant design for localising sound directions
19 Aug 2021 Animal experiments demonstrated the need for new cochlear implant design for localising sound directions
Cochlear implants help deaf patients in hearing, yet the current technology remains far from perfect. A research team led by scientists from CityU has shown that neonatally deafened rats could be trained with cochlear implant stimulation to restore the ability to locate the directions of sound origins...
(Photo source: Rosskothen-Kuhl et al/ DOI number: 10.7554/eLife.59300)
Discovery of ray sperms’ unique swimming motion and demonstration with bio-inspired robot
9 Jun 2021 Discovery of ray sperms’ unique swimming motion and demonstration with bio-inspired robot
It is generally agreed that sperms “swim” by beating or rotating their soft tails. However, a research team co-led by Dr Jiahai Shi has discovered that ray sperms move by rotating both the tail and the head. The team further investigated the motion pattern and demonstrated it with a robot. Their study has expanded the knowledge on the microorganisms’ motion and provided inspiration for robot engineering design...
Breakthrough in battling Triple-Negative Breast Cancer
20 May 2021 Breakthrough in battling Triple-Negative Breast Cancer
A research team led by Dr Rebecca Chin and Dr Xin Wang has identified a set of specific super-enhancers that stimulate the activity of the Triple-Negative Breast Cancer (TNBC) genes, and that deleting certain specific super-enhancers can reduce tumour growth. The findings may help discover new effective drug targets for TNBC patients to improve their survival chance...
CityU wins 6 golds at Inventions Geneva Evaluation Days
18 May 2021 CityU wins 6 golds at Inventions Geneva Evaluation Days
Dr Jianbo Yue and Dr Xi Yao received Gold Medals at the Inventions Geneva Evaluation Days (IGED) 2021, a virtual edition of the International Exhibition of Inventions of Geneva...
Discovering the Neural Mechanisms Between Chronic Pain and Cognitive Deficits
3 May 2021 Discovering the Neural Mechanisms Between Chronic Pain and Cognitive Deficits
While the clinical connection between chronic pain and increases in levels of anxiety, depression, cognitive dysfunction has long been established, the underlying mechanisms of brain neural networks remain less understood. Prof. Ying Li has achieved breakthroughs by unveiling the secrets of brain molecules and tissue – astrocytes and myelin – in the central nervous system...
From Memory Formation to Treatment of Brain Disorders
28 Apr 2021 From Memory Formation to Treatment of Brain Disorders
How memories are formed has long been a fundamental question for neuroscientists. Studies by Prof. Jufang He have shed light on the crucial role of a key neuromodulator, called cholecystokinin (CCK), in memory forming in the neocortex. As a result of the discovery of CCK›s functions, Prof. He is developing a treatment strategy to alleviate epilepsy, tinnitus, Alzheimer›s disease, and other brain disorders...
Targeted genetic analysis helps dissect disease inheritance
26 Apr 2021 Targeted genetic analysis helps dissect disease inheritance
An international research team co-led by Dr Jian Yan has developed a high-throughput biological assay technique that provides valuable data for finding type-2 diabetes key biomarkers for diagnostics and treatment...
CityU biologists discover super-enhancers that switch on breast cancer genes
15 Apr 2021 CityU biologists discover super-enhancers that switch on breast cancer genes
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the major treatment option, but the clinical result is unsatisfactory. A research team led by Dr Rebecca Chin and Dr Xin Wang has identified and characterised a set of specific super-enhancers that stimulate the activity of the related critical cancer genes...
See all news