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Recent Publications
Wan, Y. C. E., Liu, J., Zhu, L., Kang, T. Z. E., Zhu, X., Lis, J., Ishibashi, T., Danko C. G., Wang, X. & Chan, K. M. (2020). The H2BG53D oncohistone directly upregulates ANXA3 transcription and enhances cell migration in pancreatic ductal adenocarcinoma. Signal Transduction and Targeted Therapy, 5: 106.

doi: 10.1038/s41392-020-00219-2
Wan, Y. C. E., Leung, T. C. S., Ding, D., Sun, X., Liu, J., Zhu, L., Kang, T. Z. E., Yang, D., Zhang, Y., Zhang, J., Qian, C., Huen, M. S. Y., Li, Q., Chow, M. Z. Y., Zheng, Z., Han, J., Goel, A., Wang, X., Ishibashi, T., & Chan, K. M. (2020). Cancer-associated histone mutation H2BG53D disrupts DNA–histone octamer interaction and promotes oncogenic phenotypes. Signal Transduction and Targeted Therapy, 5: 27.

doi: 10.1038/s41392-020-0131-0
Wang, Y., Wang, Z., Xie, K., Zhao, X., Jiang, X., Chen, B., Han, Y., Lu, Y., Huang, L., Zhang, W., Yang, Y. & Shi, P. (2020). High-Efficiency Cellular Reprogramming by Nanoscale Puncturing. Nano Letters.

doi: 10.1021/acs.nanolett.0c01979
Hua, C., Wang, T., Shao, X., Xie, Y., Huang, H., Liu, J., Zhang, W., Zhang, Y., Ding, Y., Jiang, L., Wang, X. & Deng, X. (2020). Pseudomonas syringae dual‐function protein Lon switches between virulence and metabolism by acting as both DNA ‐binding transcriptional regulator and protease in different environments. Environmental Microbiology.

doi: 10.1111/1462-2920.15067
Wang, Z., Qi, L., Yang, Y., Lu, M., Xie, K., Zhao, X., Cheung, E. H. C., Wang, Y., Jiang, X., Zhang, W., Huang, L., Wang, X. & Shi, P. (2020). High-throughput intracellular biopsy of microRNAs for dissecting the temporal dynamics of cellular heterogeneity. ScienceAdvances, 6(24): eaba4971.

doi: 10.1126/sciadv.aba4971
Huang, L., Deighan, P., Jin, J., Li, Y., Lee, E., Mo, S. S., Hoover, H., Abubucker, S., Finkel, N., McReymolds, L., Hochschild, A. & Lieberman, J. (2020). Tombusvirus p19 captures RNase III-cleaved double-stranded RNAs formed by overlapping sense and antisense transcripts in E. coli. bioRxiv & mBio, 11(3):e00485-20.

doi: 10.1101/510842
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News

Intracellular biopsy technique for fast microRNAs profiling in living cells
19 Jun 2020 Intracellular biopsy technique for fast microRNAs profiling in living cells
MicroRNAs (miRNAs) are gaining more attention in researches of different human diseases (e.g. cancer) because changes in miRNA expression are frequently associated with abnormal cellular functions. To achieve fast and highly sensitive profiling of miRNAs, a research team from CityU has developed a novel intracellular biopsy technique that isolates targeted miRNAs from living cells within around 10 minutes by using diamond nanoneedles...
Data science and Covid-19: let the numbers talk
5 Jun 2020 Data science and Covid-19: let the numbers talk
Reflecting our growing reputation for excellence in data science, leading scholars from CityU, Harvard, MIT, Cornell, UT Austin, UC Irvine, HKU and HIT (Shenzhen) convened online for an international forum on data, statistics and Covid-19 pandemic...
(Application deadline extended) BMS introduces new master's programme in health science and management
29 Nov 2019 BMS introduces new master's programme in health science and management
The programme prepares its graduates for a range of careers in the large and interdisciplinary healthcare and management field. Graduates may work in different health services organizations or non-profit making groups, private insurance companies, public health or administration, hospitals, schools or government agencies...
New in vivo priming strategy to train stem cells can enhance cardiac repair effectiveness
15 Apr 2020 New in vivo priming strategy to train stem cells can enhance cardiac repair effectiveness
Dr Kiwon Ban, together with his collaborators, has developed a novel strategy, called in vivo priming, to “train” the stem cells to stay strong after implantation to the damaged heart via the 3D-printed bandage-like patch...
CityU estimate: Patients quarantined after symptoms for 3.5 days
5 Mar 2020 CityU estimate: Patients quarantined after symptoms for 3.5 days
A possible increase of around 60 infected cases of the novel coronavirus (COVID-19) from mid-February to mid-March is projected by Dr Sean Yuan Hsiang-yu. Whether the number of local infections will grow significantly depends on how effective the quarantine measures are at reducing the recontact rate between the high-risk individuals and other people...
Rare cells bring new hope in cancer immunotherapy
25 Feb 2020 Rare cells bring new hope in cancer immunotherapy
Unleashing the intrinsic power of the immune system to fight cancer is the focus of a research led by Dr Chow Kwan Ting, who has received the 2019 Croucher Innovation Award for her pioneering research on the anti-tumour activities of a rare immune cell type – plasmacytoid dendritic cells (pDCs)...
CityU expert assesses worst scenario for coronavirus outbreak in Hong Kong
4 Feb 2020 CityU expert assesses worst scenario for coronavirus outbreak in Hong Kong
Dr Sean Yuan Hsiang-yu estimates that the worst-case scenario for a novel coronavirus outbreak in the local community could be more than 220 individuals infected over the next two weeks after the Chinese New Year holidays...
CityU’s new blood test technology for accurate detection of cancer cells
19 Dec 2019 CityU’s new blood test technology for accurate detection of cancer cells
Groundbreaking technology that can accurately perform early screening for cancer cells and effectively monitor disease status has been successfully developed by a research team led by Prof. Michael Yang...
World-first coating developed at CityU can enhance medical, aerospace equipment
18 Dec 2019 World-first coating developed at CityU can enhance medical, aerospace equipment
A world-first self-healable anti-smudge coating successfully developed by a research team led by Dr Xi Yao lead to production costs that are 80% lower than for existing materials...
New brain studies for treating myelin-related diseases
11 Dec 2019 New brain studies for treating myelin-related diseases
A study led by Prof. Ying Li reveals for the first time that schema-like learning can foster the growth and regeneration of brain myelin, thereby enhancing the synchrony of neural networks...
First dual stem cell therapy brings new hope for cardiac repair
10 Sep 2019 First dual stem cell therapy brings new hope for cardiac repair
A research team featuring an expert from the University has developed a novel dual approach for the first time for concurrently rejuvenating both the cardiac muscle and vasculature of the heart by utilising two types of stem cells. The results give hope for a new treatment for repairing myocardial infarction (MI) heart...
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