Itaconic Acid Production by Methylorubrum Extorquens AM1
The inventors successfully engineered M. extorquens AM1 to produce itaconic acid using acetate and methanol as feedstock, by expressing a heterologous codon-optimized gene that encodes cis-aconitic acid decarboxylase derived from Aspergillus terreus from a pTE101-based plasmid.
Prof. LEE Patrick Kwan Hon, Dr. LIM Chee Kent
- Itaconic acid
- Methanol feedstock
- Acetate Feedstock
- Biotechnology
- Biosynthesis