Sensor for Liquid Biopsy and Its Method of Making, and Method of Non-Invasive Liquid Biopsy
The invention involves the precise detection of enhanced exosomal CD44 by sensitive non-invasive titanium nitride (TiN) nanoholes- localized surface plasmon resonance (TiN-NH-LSPR) - and TiN-NH discs immunocapture- atomic force microscopy (TIC-AFM) biosensors, demonstrating this may be a promising liquid biopsy method in both detecting the malignant transition of GMs and potentially determining the therapeutic efficacy of anti-glioma agents.
Prof. LEE Youngjin, Prof. Lawrence WU, Dr. THAKUR Abhimanyu, Dr. NG Siu Pang, Mr. XU Chen
- Biomarker cancer
- Diagnostics
- Exosome detection
- Glioma cells
- Liquid biopsy
- Cancer Diagnosis
- Cancer Therapy
- Exosome research
- Nanovesicle research