[photo caption: Common deformation pathways in RNA and DNA.]
DNA and RNA deformations play crucial roles in biological processes, such as DNA packaging and nucleic acid recognition by proteins. The research team led by Professor Liang Dai, Associate Professor from CityU’s Department of Physics, revealed universal deformation mechanisms governing eight phenomena: DNA and RNA deformations induced by salt, temperature change, stretching force, and protein binding. Based on the unified physical mechanism revealed, their theory can quantitatively explain experimental results of DNA and RNA deformations induced by salt, temperature change, stretching force, and protein binding.
To learn more, please check out the recent article on Times Higher Education (THE), titled "Understanding Universal DNA and RNA Deformation Mechanisms".
17 August 2023