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Method of Treating Breast Cancer in a Subject by Inhibiting Nip7 and a Pharmaceutical Composition Comprising a Nip7 Inhibitor
This patent introduces a novel CRISPR/Cas9-based gene-editing approach to inhibit NIP7 expression in TNBC cells.
Prof. CHIN Rebecca Y M, Dr. TIAN Ye
  • NIP7 Inhibition
  • CRISPR/Cas9 Gene Editing
  • gRNA
  • Triple-negative Breast Cancer (TNBC)
  • Gene Expression Regulation
  • Pharmaceuticals
  • Precision Medicine
  • Cancer Therapy
  • Genetic Engineering
TRL
4
Method of Treating Breast Cancer in a Subject by Inhibiting TUBB2B
Expression of the protein TUBB2B has been detected in several cancer types, including TNBC. This makes TUBB2B a promising target for therapies aimed specifically at TNBC.
Prof. CHIN Rebecca Y M, Dr. HU Jianyang, Dr. HE Qingling
  • RNA Interference
  • Short Hairpin RNA
  • TUBB2B Inhibition
  • Protein Expression
  • Cancer Therapy
  • Targeted Therapy
TRL
4
Guide RNA Molecule and Method for Treating Cancer
This invention can treat diseases associated with abnormal TCOF1 gene expression, in particular TNBC.
Prof. CHIN Rebecca Y M, Dr. WANG Xin, Dr. HU Jianyang
  • CRISPR/Cas9 Gene Editing
  • Cancer Cell Targeting
  • Guide RNA Design
  • Breast Cancer Treatment
  • Cancer Therapy
  • Disease Therapy
TRL
5

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