PhD students SI Wen and MA Xin, under the supervision of Professor YANG Guan, represented the lab at the 20th World Immune Regulation Meeting (WIRM 2026) held in Davos, Switzerland. Both scholars showcased their latest findings in the field of immunology, highlighting their group’s ongoing contributions to understanding the interface between innate signaling pathways, immune regulation, and microbial influences in autoimmunity.
The World Immune Regulation Meeting is a renowned annual international conference that brings together leading scientists and clinicians to discuss the most recent advances in immune mechanisms, tolerance, and therapy. Since its inception, WIRM has served as a key platform fostering collaboration and knowledge exchange among researchers working on immune regulation, neuroinflammation, and translational immunology.
During the conference, Wen delivered an oral presentation on her research into dendritic cells (DCs). Her study focuses on the mechanisms by which dendritic cell–intrinsic MyD88 signaling regulates monocyte-derived dendritic cell (moDC) function and Treg responses during autoimmune neuroinflammation. Meanwhile, Xin presented her findings in the poster session, where she shared her work on identifying myelin antigen mimics derived from the human gut microbiota using computational screening approaches. Her research sheds light on how microbial components may contribute to the development of autoimmune diseases through molecular mimicry mechanisms.
Their participation in WIRM 2026 reflects the lab’s active engagement in cutting-edge immunological research and its strong international presence. Their research underscores the group’s commitment to addressing fundamental questions in immune regulation and highlights the broader scientific significance of their work in advancing our understanding of how innate immune signaling and microbial factors shape autoimmune pathogenesis.
Wen doing her presentation
Xin and her poster
Xin and Wen at the conference venue