In the era of globalization and digital innovation, firms need to smartly develop their strategy and tactical plan to respond to the dynamic business and technology environments. Meanwhile, many firms struggle with receiving strategic benefits from information systems and technology (IS/IT) investments, given the complexity and uncertainty of the IS/IT services and infrastructure. This course introduces firms’ business model, nature of IS/IT innovation and infrastructure, and a set of methods for strategic and tactical planning of global business IS/IT. Moreover, this course also discusses the characteristics and challenges of managing global business and incorporates such information in firms’ strategic and tactical planning. Learning this course can help your own firm or business build a digital strategy with a global view, so that you can not only harness digital innovation in achieving alignment with the firm’s current business strategy, but also leverage digital innovation to create new strategies and business capabilities.