This course aims to give students a comprehensive overview of (i) different classes of naturally occurring organic molecules (termed "natural products") produced by microorganisms and plants, (ii) organic reactions utilized in natural product biosynthesis, and (iii) genes and enzymes involved therein. Students will also learn how to use bioinformatic tools to link biosynthetic genes to natural products and vice versa. Altogether, students will be able to classify and describe natural products and provide plausible biosynthetic schemes for given compounds as well as genes/enzymes required for their biosynthesis. This course will also help students understand chemical reactions occurring in other biological systems (e.g., in humans) or design biosynthetic pathways to afford compounds of interest.