The course aims to teach students about fundamental knowledge and technology of gene therapy and genetic engineering. Gene therapy related research and applications have become more and more popular and important in medical and biomedical areas. This course is developed to deliver the fundamental knowledge about gene therapy and genetic engineering with the typical applications. This course is mainly designed to emphasize on basic concepts and focus on the application of them – how to translate biological sciences into biomedical engineering.

This course is set up in such a way that students can understand this interdisciplinary subject with minimal background. Its major components include: Definitions of Gene Therapy and Genetic Engineering; Gene Delivery: Viral and Non-Viral Vectors; Therapeutic Antisense; Basic Gene Editing Technology; and typical clinical applications, such as CAR-T. It will be delivered to emphasize biomedical engineering perspectives, including the related instrumentation and methodologies for gene sequencing, medical/molecular imaging and so on.