Traditional business principles are evolving in order to align with the rise of blockchain, web3, Artificial Intelligence (AI), and other technologies and innovation that continues to drive the business space. This course will cover fundamental AI principles, including the technology and the practical applications, and unique characteristics of innovation in the current business environment. From understanding generative AI technologies like large language models, text-to-images systems, and digital human technologies, to exploring specific applications, students gain a holistic understanding of AI's transformative potential and the impact on businesses. Through interactive sessions and case studies, students will develop skills to assess market dynamics, craft strategic AI-driven initiatives, and make informed business decisions. By course completion, students are equipped to design and implement AI-powered solutions, positioning themselves as adept navigators of the evolving AI landscape in business.