This course provides a coherent, interdisciplinary account of how design works, and how to do it better. It covers foundational design theories, methods, and principles that transcend conventional disciplinary boundaries. Through a blend of lectures and hands-on design projects, students will learn how design science intersects with practical applications across diverse fields, including engineering, architecture, medicine, business, policy, and etc. Lectures will introduce a wide range of techniques for empathy, ideation, prototyping, testing, optimization, and etc throughout the design process. Particularly, students will learn to treat AI as both material and partner in design: using generative and agentic systems to widen search and tighten iteration, grounded in verification and governance. Design projects will challenge students to recognize emerging societal issues as design opportunities, leading to the creation of human-centred products, services, and systems that shape the future. By integrating theoretical knowledge with experiential learning, this course helps students develop a holistic understanding of design's transformative power, fostering innovation and leadership.