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Dr. RUAN Yuefei Phoebe (阮悦斐博士)

BSc (Nankai), MPhil (Nankai), PhD (CityU)

Research Assistant Professor (SKLMP)

Visiting Assistant Professor (CHEM)

Contact Information

Office: B6703 YEUNG
Phone: 34427833
Fax: 34420524
Email: yruan8@cityu.edu.hk

Research Interests

  • Analytical Chemistry
  • Emerging Chemicals of Concern
  • Marine Pollution
  • Ecotoxicology
  • Environmental Risk Assessment
Yuefei Ruan obtained her Bachelor's and Master's degrees at Nankai University in 2011 and 2014, respectively. She received doctoral and postdoctoral training at City University of Hong Kong (CityU) from 2014 to 2019, supervised by Prof. Paul Kwan-sing Lam. Then she joined State Key Laboratory of Marine Pollution (SKLMP), CityU as Research Fellow until April 2021. She is currently working as Research Assistant Professor (研究型助理教授) at SKLMP, holding a concurrent appointment as Visiting Assistant Professor at Department of Chemistry (CHEM), CityU.

Research Insterests
Environmental Analytical Chemistry
Sensitive quantitative methods for the trace analysis of organic pollutants; Suspect and non-target screening for the identification of novel/unknown organic pollutants; Enantiomeric chromatographic separations; Extraction and clean-up strategies for complex environmental matrices.
Emerging Chemicals of Concern
Including but not limited to: Halogenated flame retardants (HFRs); Per- and polyfluoroalkyl substances (PFASs); Pharmaceuticals and personal care products (PPCPs); Phycotoxins/algal toxins; Bisphenol analogues; Chiral/stereospecific pollutants/contaminants.
Marine Pollution
Coastal, estuarine, and marine ecosystems; Occurrence, transport, and fate; Source and sink; Phase partitioning; Spatiotemporal trend; Trophic transfer; Bioindicator/sentinel species.
Ecotoxicology and Environmental Risk Assessment
Toxicodynamics and toxicokinetics; Suspected metabolites; Model species; Hazard quotient; Probabilistic approach; Species sensitivity distribution.


Selected Publications (*corresponding author)

  • Wang Q, Ruan Y*, Jin L, Kot BC, Leung KM, Lam PK*, 2023. Temporal trends and suspect screening of halogenated flame retardants and their metabolites in blubbers of cetaceans stranded in Hong Kong waters during 2013−2020. Environmental Science & Technology, 57(25), 9298−9308. https://doi.org/10.1021/acs.est.3c00684
  • Lao J-Y, Ruan Y*, Leung KM, Zeng EY, Lam PK*, 2023. Review on age-specific exposure to organophosphate esters: Multiple exposure pathways and microenvironments. Critical Reviews in Environmental Science and Technology, 53(7), 803−826. https://doi.org/10.1080/10643389.2022.2087428
  • Wang Q, Ruan Y*, Jin L, Tao LS, Lai H, Li G, Yeung LW, Leung KM, Lam PK*, 2023. Legacy and emerging per- and polyfluoroalkyl substances (PFASs) in a subtropical marine food web: Suspect screening, isomer profile, and identification of analytical interference. Environmental Science & Technology, 57(22), 8355−8364. https://doi.org/10.1021/acs.est.3c00374
  • Liu Y, Wang Q, Ma L, Jin L, Zhang K, Tao D, Wang W-X, Lam PK, Ruan Y*, 2023. Identification of key features relating to the coexistence mechanisms of trace elements and per-and polyfluoroalkyl substances (PFASs) in marine mammals. Environment International, 178, 108099. https://doi.org/10.1016/j.envint.2023.108099
  • Wang Q, Ruan Y*, Yuen CN, Lin H, Yeung LW, Leung KM, Lam PK*, 2023. Tracing per- and polyfluoroalkyl substances (PFASs) in the aquatic environment: Target analysis and beyond. TrAC Trends in Analytical Chemistry, 169, 117351. https://doi.org/10.1016/j.trac.2023.117351
  • Jin L, Wang Q, Yan M, Gu J, Zhang K*, Lam PK, Ruan Y*, 2023. Enantio-specific uptake and depuration kinetics of chiral metoprolol and venlafaxine in marine medaka (Oryzias melastigma): Tissue distribution and metabolite formation. Environmental Science & Technology, 57(11), 4471−4480. https://doi.org/10.1021/acs.est.2c08379
  • Lao J-Y, Huang G, Zhang K, Wang Q, Xu S, Ruan Y*, Wu J, Leung KM, Zeng EY, Huang B, Lam PK*, 2023. Anthropogenic impacts on organophosphate ester loads to an urban estuary in South China. ACS ES&T Water, 3(1), 203−212. https://doi.org/10.1021/acsestwater.2c00496
  • Ruan Y, Sun H*, Lu Y, Zhang Y, Xu J, Zhu H, He Y, 2022. Evaluating phospholipid− and protein−water partitioning of two groups of chemicals of emerging concern: Diastereo- and enantioselectivity. Journal of Hazardous Materials, 430: 128499. https://doi.org/10.1016/j.jhazmat.2022.128499
  • Wu R, Ruan Y*, Huang G, Li J, Lao J-Y, Lin H, Liu Y, Cui Y, Zhang K, Wang Q, Wu J, Huang B, Yan M, Lam PK*, 2022. Source apportionment, hydrodynamic influence, and environmental stress of pharmaceuticals in a microtidal estuary with multiple outlets in South China. Environmental Science & Technology, 56(16), 11374−11386. https://doi.org/10.1021/acs.est.2c02384
  • Wang Q, Ruan Y*, Jin L, Lin H, Yan M, Gu J, Yuen CN, Lam PK*, 2022. Tissue-specific uptake, depuration kinetics, and suspected metabolites of four emerging per- and polyfluoroalkyl substances (PFASs) in marine medaka. Environmental Science & Technology, 56(10), 6182−6191. https://doi.org/10.1021/acs.est.1c07643
  • Li J, Ruan Y*, Wu R, Cui Y, Shen J, Mak YL, Wang Q, Zhang K, Yan M, Wu J, Lam PK, 2022. Occurrence, spatial distribution, and partitioning behavior of marine lipophilic phycotoxins in the Pearl River Estuary, South China. Environmental Pollution, 310, 119875. https://doi.org/10.1016/j.envpol.2022.119875
  • Wang Q, Ruan Y*, Jin L, Lu G, Ma L, Yeung LW, Wang WX, Lam PK*, 2022. Oysters for legacy and emerging per- and polyfluoroalkyl substances (PFASs) monitoring in estuarine and coastal waters: Phase distribution and bioconcentration profile. Science of the Total Environment, 846, 157453. https://doi.org/10.1016/j.scitotenv.2022.157453
  • Lao J-Y, Lin H, Qin X, Ruan Y*, Leung KM, Zeng EY, Lam PK*, 2022. Insights into the atmospheric persistence, transformation, and health implications of organophosphate esters in urban ambient air. Environmental Science & Technology, 56(17), 12003−12013. https://doi.org/10.1021/acs.est.2c01161
  • Lin H, Lao J-Y, Wang Q, Ruan Y*, He Y, Lee PK, Leung KM, Lam PK*, 2022. Per- and polyfluoroalkyl substances in the atmosphere of waste management infrastructures: Uncovering secondary fluorotelomer alcohols, particle size distribution, and human inhalation exposure. Environment International, 167, 107434. https://doi.org/10.1016/j.envint.2022.107434
  • Lao J-Y, Wu R, Cui Y, Zhou S, Ruan Y*, Leung KM, Wu J, Zeng EY, Lam PK*, 2022. Significant input of organophosphate esters through particle-mediated transport into the Pearl River Estuary, China. Journal of Hazardous Materials, 438, 129486. https://doi.org/10.1016/j.jhazmat.2022.129486
  • Li J, Ruan Y*, Mak YL, Zhang K, Leung KM, Lam JC, Lam PK*, 2021. Occurrence and trophodynamics of marine lipophilic phycotoxins in a subtropical marine food web. Environmental Science & Technology, 55(13), 8829−8838. https://doi.org/10.1021/acs.est.1c01812
  • Wang Q, Ruan Y*, Jin L, Zhang X, Li J, Wei S, He Y, Lam JC, Lam PK*, 2021. Target, non-target and suspect screening and temporal trend of per- and polyfluoroalkyl substances in marine mammals from the South China Sea. Environmental Science & Technology, 55: 1045−1056. https://doi.org/10.1021/acs.est.0c06685
  • Wu R, Ruan Y*, Lin H, Feng H, Lam PK*, 2021. Occurrence and fate of psychiatric drugs in wastewater treatment plants in Hong Kong: wastewater-based epidemiology and enantiomeric profiling. ACS ES&T Water, 1: 542−552. https://doi.org/10.1021/acsestwater.0c00081
  • Feng H, Cheng Y, Ruan Y*, Tsui MM, Wang Q, Jin J, Wu R, Zhang H, Lam PK, 2021. Occurrence and spatial distribution of legacy and novel brominated flame retardants in seawater and sediments of the South China Sea. Environmental Pollution, 271: 116324. https://doi.org/10.1016/j.envpol.2020.116324
  • Lao J-Y, Li T-Y, Wu R, Ruan Y*, Zeng EY, Wu J, Lam PK*, 2021. Tracing human footprint and the fate of atmospheric polycyclic aromatic hydrocarbons over the Pearl River Estuary, China: Importance of particle size. Science of the Total Environment, 767: 144267. https://doi.org/10.1016/j.scitotenv.2020.144267
  • Ruan Y, Lin H, Zhang X, Wu R, Zhang K, Leung KM, Lam JC*, Lam PK*, 2020. Enantiomer-specific bioaccumulation and distribution of chiral pharmaceuticals in a subtropical marine food web. Journal of Hazardous Materials, 394: 122589. https://doi.org/10.1016/j.jhazmat.2020.122589
  • Wang Q, Ruan Y*, Lin H, Lam PK, 2020. Review on perfluoroalkyl and polyfluoroalkyl substances (PFASs) in the Chinese atmospheric environment. Science of the Total Environment, 737: 139804. https://doi.org/10.1016/j.scitotenv.2020.139804
  • Ruan Y, Wu R, Lam JC*, Zhang K, Lam PK*, 2019. Seasonal occurrence and fate of chiral pharmaceuticals in different sewage treatment systems in Hong Kong: Mass balance, enantiomeric profiling, and risk assessment. Water Research, 149: 607−616. https://doi.org/10.1016/j.watres.2018.11.010
  • Ruan Y, Zhang K, Lam JC*, Wu R, Lam PK*, 2019. Stereoisomer-specific occurrence, distribution, and fate of chiral brominated flame retardants in different wastewater treatment systems in Hong Kong. Journal of Hazardous Materials, 374: 211−218. https://doi.org/10.1016/j.jhazmat.2019.04.041
  • Ruan Y, Zhang K*, Wu C, Wu R, Lam PK, 2019. A preliminary screening of HBCD enantiomers transported by microplastics in wastewater treatment plants. Science of the Total Environment, 674: 171−178. https://doi.org/10.1016/j.scitotenv.2019.04.007
  • Ruan Y, Lalwani D, Kwok KY, Yamazaki E, Taniyasu S, Kumar JN, Lam PK, Yamashita N*, 2019. Assessing exposure to legacy and emerging per- and polyfluoroalkyl substances via hair – the first nationwide survey in India. Chemosphere, 229: 366−373. https://doi.org/10.1016/j.chemosphere.2019.04.195
  • Ruan Y, Zhang X, Qiu J-W, Leung KM, Lam JC*, Lam PK*, 2018. Stereoisomer-specific trophodynamics of the chiral brominated flame retardants HBCD and TBECH in a marine food web, with implications for human exposure. Environmental Science & Technology, 52: 8183−8193. https://doi.org/10.1021/acs.est.8b02206
  • Ruan Y, Lam JC*, Zhang X, Lam PK*, 2018. Temporal changes and stereoisomeric compositions of 1,2,5,6,9,10-hexabromocyclododecane (HBCD) and 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane (TBECH) in marine mammals from the South China Sea. Environmental Science & Technology, 52: 2517−2526. https://doi.org/10.1021/acs.est.7b05387


Last update date : 01 Nov 2023