Abstract
Mouse model has been used for testing new drugs for years although it is costly. Recently, zebrafish has been identified as an important vertebrate model for studying the development of embryos and human diseases. When compared with mammalian models, experimental results showed that zebrafish embryos exhibited similar responses to drugs for cardiovascular diseases, anti-angiogenesis and anti-cancer. This suggests that zebrafish model can be used as the bridge between in vitro model and in vivo model in the drug discovery and screening process. In addition, pollutants can induce similar pathological responses in zebrafish as well as in other mammalian models.
Based on these discoveries, we have developed a set of proprietary tools for drug screening and pollutant testing. The bioassay, combining these proprietary tools and zebrafish embryos with unique advantages, provides a cost-effective, economical and speedy solution for the testing on drug action, toxicity and environmental pollutants.

Contact Information
Mr H Y Wong
Director, Technology Transfer Office
City University of Hong Kong
83 Tat Chee Avenue
Kowloon, Hong Kong
Tel : (852) 2788 8428
Fax : (852) 2788 9119
Email : hy.wong@cityu.edu.hk